Soft tissue sarcomas are malignant tumors that may arise in any of the mesodermal tissues of the extremities (50%), trunk and retroperitoneum (40%), or the head and neck (10%). 

Effective treatment of retroperitoneal sarcomas requires removal of all gross disease while sparing adjacent viscera not invaded by tumor. The prognosis for patients with high-grade retroperitoneal sarcomas is less favorable than for patients with tumors at other sites, partly because of the difficulty in completely resecting these tumors and the limitations placed on high-dose radiation therapy.(see picture)

Complete surgical resection is often difficult for sarcomas of the retroperitoneum due to large size before detection and anatomic location. see NCCN guidelines.

sarc_reto_sum.gif (14333 bytes)

some other studies are noted elsewhere:

sarc_retro_survival.gif (14848 bytes)

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