Soft tissue sarcomas are malignant tumors that may arise in any of the
mesodermal tissues of the extremities (50%), trunk and
retroperitoneum (40%), or the head and neck (10%).
Effective treatment of retroperitoneal sarcomas requires removal of all gross disease while sparing adjacent viscera not invaded by tumor. The prognosis for patients with high-grade retroperitoneal sarcomas is less favorable than for patients with tumors at other sites, partly because of the difficulty in completely resecting these tumors and the limitations placed on high-dose radiation therapy.(see picture) Complete surgical resection is often difficult for sarcomas of the retroperitoneum due to large size before detection and anatomic location. see NCCN guidelines. |
some other studies are noted elsewhere: |